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Frontiers in Emerging Multidisciplinary Sciences

Open Access Peer Review International
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Mesotherapy and Biorevitalization in Young Skin Care

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Bagdasarian Goar Karenovna 1
4 Beauty Salon Alexander Lvovich Volchenkov, Sole Proprietor Moscow, Russia

Abstract

This article provides a systematic analysis and comparative evaluation of mesotherapy and biorevitalization as the main minimally invasive approaches to treating young skin (25-35 years). This research is relevant due to the steady growth of the aesthetic medicine industry, a shift in consumer interest toward preventive interventions ("prejuvenation"), and a 46% expansion of the biorevitalization segment in the Russian market by 2024. The aim of the study is to compare the effectiveness of these methods as monotherapy and as part of combination protocols in the prevention and correction of early manifestations of chrono- and photo-induced changes. The methodological framework includes a systematic literature review in Scopus/Web of Science databases, representing the most relevant research results. The obtained data confirm that biorevitalization is a basic procedure for restoring the dermis's water reserve, significantly increasing skin hydration levels by 43.7% (p<0.05). The effectiveness of mesotherapy is determined by its composition, which is based on polyrevitalizing complexes (in particular, NCTF 135HA), demonstrating a significant improvement in structural characteristics, increasing dermal density by 24%. A study of combined protocols (chemical peeling + mesotherapy) revealed a pronounced synergism, leading to a 79% increase in skin elasticity, which exceeds the results of monotherapy. Finally, a conclusion is made regarding the feasibility of differentiated tactics for young patients: biorevitalization as a tool for global rehydration, mesotherapy in combination with peels for targeted solutions to specific problems, including post-acne and dyschromia. The information presented in this article will be of interest to practicing dermatologists and cosmetologists focused on developing scientifically based protocols for the care of young patients.

How to Cite

Karenovna, B. G. (2025). Mesotherapy and Biorevitalization in Young Skin Care. Frontiers in Emerging Multidisciplinary Sciences, 2(12), 29–37. Retrieved from https://irjernet.com/index.php/fems/article/view/357
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